A clinico-pathological study was made on a series of 41 malignant ovarian tumors treated at the Department of Obstetrics and Gynecology, Kang Nam Sacred-Heart Hospital, Hallym University from the January 1, 1985 to December 31, 1994.
@ES The results obtained were as follows:
@EN 1. The incidence of malignant ovarian tumors among all ovarian tumors was 7.1%.
2. Age distribution of malignant ovarian tumors showed the highest frequency in 3rd, 4th decade and average age was 42 years old.
3. The frequency of nulliparity was 36.6% and the primary infertility rate was 4.6%.
4. Previous menstrual cycles were normal in 48.8%, postmenopause in 29.3%, physiologic amenorrhea in 2.4% and some menstrual abnormalities in 19.5%.
5. As to the subjective symptoms of all malignant ovarian tumors, palpable mass in the lower abdomen was noticed in 70.7%, lower abdominal pain in 63.4%, abdominal distension in 19.5%, urinary symptoms in 19.5% and menstrual abnormalities in
12.2%.
6. According to the clinical stages based on FIGO classification, stage I was seen in 51.2%, stage II in 9.8%, stage III in 26.8% and stage IV in 9.8%.
7. According to the histopathological classification of WHO, epithelial tumor was found in 61%, non-epithelial tumor in 31.8%, metastatic tumor in 7.2% and among them serous cystadenocarcinoma was found in 26.8%, mucinous cystadenocarcinoma in
19.6%,
endometrioid adenocarcinoma in 12.2%, clear cell carcinoma in 2.4%, dysgerminoma in 12.2%, malignant teratoma in 98% and Krukenberg tumor in 2.4%.
8. Bilaterality was noted in 31.7% by microscopic examination.
9. Treatment was surgical primarily with or without omentectomy, which was performed in 51.2% in our study. Postoperative complications were noticed in several cases as follows; fever, ileus, wound infection and UTI.
10. Adjuvant chemotherapy was performed on 20 cases(48.8%) and the complication of combined chemotherapy was seen as follows; nausea and vomiting, alopecia, leukopenia, thrombocytopenia, anemia, and hepatotoxicity.
11. Because of insufficient follow-up, 5 year survival rate could not be calculated, and only 6 cases of 5 year survival were recognized.
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